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Among participants on tirzepatide, the rate of new-onset type 2 diabetes was dramatically lower: 0.4% for the 15 mg group compared to 13.3% for placebo over three years

A Phase 1b study first established that co-administering cagrilintide with semaglutide 2.4 mg was tolerable and characterized cagrilintides pharmacokinetics, including its multi-day half-life of roughly 159195 hours